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Considerations for the Introduction of TLD in National Programs: PEPFAR Guidance on Developing Clinical and Programmatic Recommendations

This considerations document is intended to inform clinical and programmatic decision-making as country programs introduce TLD.

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This document supports country program managers to develop clinical guidance and implementation plans for the introduction of the fixed-dose combination tablet of tenofovir, lamivudine and dolutegravir (TLD). It combines summaries of current normative guidance, available evidence, and programmatic considerations to inform the practical decisions that countries will need to make to develop comprehensive guidance on the use of TLD.

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ARV Information

ALL AFRICA

HCW Training on the Introduction of DTG for the Treatment of HIV Supplemental Module: Pregnancy and Breastfeeding

A pregnancy and breastfeeding supplemental module to the HCW Training Package which can be adapted at the country level to train providers during the transition to TLD.

ALL AFRICA

HCW Training on the Introduction of DTG for the Treatment of HIV Supplemental Module: Toxicity Monitoring

A toxicity monitoring supplemental module to the HCW Training Package which can be adapted at the country level to train providers during the transition to TLD.

All Africa

HCW Training on the Introduction of DTG for the Treatment of HIV

A five module training package which can be adapted at the country level to train providers during the transition to TLD.

All Africa

Considerations for the Introduction of TLD in National Programs: PEPFAR Guidance on Developing Clinical and Programmatic Recommendations

This considerations document is intended to inform clinical and programmatic decision-making as country programs introduce TLD.

All Africa

Country Readiness Assessment

Tool to assess the capacity and readiness of country programs to introduce, manage and monitor new optimized ARVs.

All Africa

Checklist to Guide Optimal ARV Introduction

A brief overview of the activities country programs need to consider and plan for to ensure successful transition to new ARVs.

All Africa

ICAP Grand Rounds Webinar on ART Optimization

Overview of rationale for optimization, summary of recent clinical evidence, and country guidance to support transition to new ART regimens.

All Africa

ARV Implementation Guide

Overview of OPTIMIZE including menu of services available to support country transitions to optimal ARVs.

All Africa

Impact Overview

Describes clinical and financial benefits of simpler, safer, and more affordable HIV treatment through ART optimization.

Case studies

All Africa

First Line Transition Case Study

Case study of previous transitions to new first line antiretroviral regimens.

Country Needs Assessments

Kenya

Kenya Situational Analysis

Assessment of Kenya's national capacity and readiness across four functional domains.

Mozambique

Mozambique Needs Assessment

Assessment of Mozambique’s capacity and readiness to introduce optimal ARVs.

South Africa

South Africa Needs Assessment

Assessment of South Africa’s capacity and readiness to introduce optimal new ARVs.

Toolkit & Guidance documents

ALL AFRICA

HCW Training on the Introduction of DTG for the Treatment of HIV Supplemental Module: Pregnancy and Breastfeeding

A pregnancy and breastfeeding supplemental module to the HCW Training Package which can be adapted at the country level to train providers during the transition to TLD.

ALL AFRICA

HCW Training on the Introduction of DTG for the Treatment of HIV Supplemental Module: Toxicity Monitoring

A toxicity monitoring supplemental module to the HCW Training Package which can be adapted at the country level to train providers during the transition to TLD.

All Africa

HCW Training on the Introduction of DTG for the Treatment of HIV

A five module training package which can be adapted at the country level to train providers during the transition to TLD.

All Africa

Considerations for the Introduction of TLD in National Programs: PEPFAR Guidance on Developing Clinical and Programmatic Recommendations

This considerations document is intended to inform clinical and programmatic decision-making as country programs introduce TLD.

All Africa